The Ramtops are the largest region in Discworld. While a lot of the towns aren't playable, there are still enough to make it interesting. There are a lot of long walks involved as well. Mostly boring walks too. The Guilds available in this region are:
There is a lot of unique shops and people in Lancre Kingdom. It's a good enough place to start as there are a number of fairly easy quests to do and there are a lot of places to acquire good equipment.
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